Panel Discussion: Leveraging Human Genetics for Hit-to-Lead Optimization & Effective GPCRTarget Discovery
Time: 2:00 pm
day: Day One
Creating target discovery platforms based on genetic human data for better hit-to-lead optimization is at the forefront of early drug discovery pipelines across biotech and pharma industries. We will explore the learnings from Regeneron’s key candidate GPR75 and how to inform, develop and expedite the drug discovery process for clinical success.
- Leveraging the UK Biobank databases to assist in genetic validation of GPCR target– the case of GPR75
- How best to select a leading candidate for optimisation and taken through for translation and clinical development?
- How to expedite the drug discovery process for clinical efficacy?