Delineating the Conformational Landscape of the Target Receptor by NMR – Insights into Activation Mechanisms & Opportunities for Drug Discovery

Time: 12:30 pm
day: Day One

Details:

• The utility of HDL- Nanodiscs for functional assays and NMR studies of functional states and dynamics
• Relating the conformational landscape to pharmacology
• Enhancing GPCR pharmacology with NMR spectroscopy to achieve region specific site and motif detection